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Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1

Amyloid diseases represent a growing social and economic burden in the developed world. Understanding the assembly pathway and the inhibition of amyloid formation is key to developing therapies to treat these diseases. The neurodegenerative condition Machado–Joseph disease is characterised by the se...

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Detalles Bibliográficos
Autores principales: Knight, Patrick D, Karamanos, Theodoros K, Radford, Sheena E, Ashcroft, Alison E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134688/
https://www.ncbi.nlm.nih.gov/pubmed/29334808
http://dx.doi.org/10.1177/1469066717729298