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Local angiotensin II contributes to tumor resistance to checkpoint immunotherapy
BACKGROUND: Current checkpoint immunotherapy has shown potential to control cancer by restoring or activating the immune system. Nevertheless, multiple mechanisms are involved in immunotherapy resistance which limits the clinical benefit of checkpoint inhibitors. An immunosuppressive microenvironmen...
Autores principales: | Xie, Guozhu, Cheng, Tan, Lin, Jie, Zhang, Lanfang, Zheng, Jieling, Liu, Ying, Xie, Guobo, Wang, Baiyao, Yuan, Yawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134794/ https://www.ncbi.nlm.nih.gov/pubmed/30208943 http://dx.doi.org/10.1186/s40425-018-0401-3 |
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