Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer

Colon cancer is a widespread pathology with complex biochemical etiology based on a significant number of intracellular signaling pathways that play important roles in carcinogenesis, tumor proliferation and metastasis. These pathways function due to the action of key enzymes that can be used as tar...

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Detalles Bibliográficos
Autores principales: Mioc, Marius, Avram, Sorin, Bercean, Vasile, Kurunczi, Ludovic, Ghiulai, Roxana M., Oprean, Camelia, Coricovac, Dorina E., Dehelean, Cristina, Mioc, Alexandra, Balan-Porcarasu, Mihaela, Tatu, Calin, Soica, Codruta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134806/
https://www.ncbi.nlm.nih.gov/pubmed/30234098
http://dx.doi.org/10.3389/fchem.2018.00373

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