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Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
Vascular endothelial growth factor receptor-2 (VEGFR2) is a key mediator of angiogenesis and therefore a promising therapeutic target in malignancies including glioblastoma multiforme (GBM). Molecular imaging of VEGFR2 expression may enable patient stratification for antiangiogenic therapy. The goal...
Autores principales: | Mitran, Bogdan, Güler, Rezan, Roche, Francis P., Lindström, Elin, Selvaraju, Ram Kumar, Fleetwood, Filippa, Rinne, Sara S., Claesson-Welsh, Lena, Tolmachev, Vladimir, Ståhl, Stefan, Orlova, Anna, Löfblom, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134937/ https://www.ncbi.nlm.nih.gov/pubmed/30214632 http://dx.doi.org/10.7150/thno.24395 |
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