The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome

Small cell carcinoma (SmCC) of the head and neck is a rare occurrence. We herein present a case of a 62-year-old female who was diagnosed with small cell cancer of the uvula. The patient developed increased body swelling, elevated blood pressure, persistent hypokalemia and new onset diabetes mellitu...

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Detalles Bibliográficos
Autores principales: Natarajan, Arjun, Abugroun, Ashraf, Khan, Amir, Jahangir, Numan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134991/
https://www.ncbi.nlm.nih.gov/pubmed/30220949
http://dx.doi.org/10.14740/wjon1130w
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author Natarajan, Arjun
Abugroun, Ashraf
Khan, Amir
Jahangir, Numan
author_facet Natarajan, Arjun
Abugroun, Ashraf
Khan, Amir
Jahangir, Numan
author_sort Natarajan, Arjun
collection PubMed
description Small cell carcinoma (SmCC) of the head and neck is a rare occurrence. We herein present a case of a 62-year-old female who was diagnosed with small cell cancer of the uvula. The patient developed increased body swelling, elevated blood pressure, persistent hypokalemia and new onset diabetes mellitus. Further workup confirmed a diagnosis of Cushing’s syndrome secondary to ectopic adrenocorticotropic hormone (ACTH) production. To our knowledge, this is only the second case of SmCC of the uvula described in literature, and the first associated with any paraneoplastic syndrome. By reporting this case, we aim to characterize the tumor clinical course and highlight the aggressive nature of its growth.
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spelling pubmed-61349912018-09-14 The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome Natarajan, Arjun Abugroun, Ashraf Khan, Amir Jahangir, Numan World J Oncol Case Report Small cell carcinoma (SmCC) of the head and neck is a rare occurrence. We herein present a case of a 62-year-old female who was diagnosed with small cell cancer of the uvula. The patient developed increased body swelling, elevated blood pressure, persistent hypokalemia and new onset diabetes mellitus. Further workup confirmed a diagnosis of Cushing’s syndrome secondary to ectopic adrenocorticotropic hormone (ACTH) production. To our knowledge, this is only the second case of SmCC of the uvula described in literature, and the first associated with any paraneoplastic syndrome. By reporting this case, we aim to characterize the tumor clinical course and highlight the aggressive nature of its growth. Elmer Press 2018-08 2018-09-06 /pmc/articles/PMC6134991/ /pubmed/30220949 http://dx.doi.org/10.14740/wjon1130w Text en Copyright 2018, Natarajan et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Natarajan, Arjun
Abugroun, Ashraf
Khan, Amir
Jahangir, Numan
The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title_full The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title_fullStr The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title_full_unstemmed The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title_short The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome
title_sort first report of small cell cancer of the uvula presenting with ectopic adrenocorticotropic hormone syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134991/
https://www.ncbi.nlm.nih.gov/pubmed/30220949
http://dx.doi.org/10.14740/wjon1130w
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