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The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium
BACKGROUNDS AND AIMS: This study aims to compare hysteroscopic and histological findings in asymptomatic postmenopausal patients with thickened endometrium. MATERIALS AND METHODS: A retrospective study involving case records of 295 asymptomatic postmenopausal women with a thickened endometrium >5...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135156/ https://www.ncbi.nlm.nih.gov/pubmed/30254927 http://dx.doi.org/10.4103/GMIT.GMIT_10_17 |
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author | Trojano, Giuseppe Damiani, Gianluca Raffaello Casavola, Vita Caroli Loiacono, Rossella Malvasi, Antonio Pellegrino, Antonio Siciliano, Valeria Cicinelli, Ettore Salerno, Maria Giovanna Battini, Lorella |
author_facet | Trojano, Giuseppe Damiani, Gianluca Raffaello Casavola, Vita Caroli Loiacono, Rossella Malvasi, Antonio Pellegrino, Antonio Siciliano, Valeria Cicinelli, Ettore Salerno, Maria Giovanna Battini, Lorella |
author_sort | Trojano, Giuseppe |
collection | PubMed |
description | BACKGROUNDS AND AIMS: This study aims to compare hysteroscopic and histological findings in asymptomatic postmenopausal patients with thickened endometrium. MATERIALS AND METHODS: A retrospective study involving case records of 295 asymptomatic postmenopausal women with a thickened endometrium >5 mm diagnosed at transvaginal ultrasound (TVS). Patients (women) underwent hysteroscopy with biopsy between 2009 and 2015, and they were followed up at National Cancer Institute of Bari and at University Hospital of Pisa. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of hysteroscopy were evaluated. RESULTS: Inclusion criteria were TVS, hysteroscopy, and endometrial biopsy. When the hysteroscopic findings were normal, a sensitivity of 100%, specificity of 98.6%, PPV of 95.2%, and NPV of 100% were achieved. For polyps and myomas, we found 100%, 98.7%, 99.5%, and 100%, respectively. In case of endometrial hyperplasia, a sensitivity of 66.7%, a specificity of 100%, a PPV of 100%, and a NPV of 98.1% were achieved. For endometrial cancer hysteroscopy, sensitivity, specificity, PPV, and NPV were 100%, 99.6%, 75%, and 100%, respectively. CONCLUSIONS: Hysteroscopy allows an accurate diagnosis in benign endometrial pathology and suspect of malignant endometrial pathology in postmenopausal women with thickened endometrium. |
format | Online Article Text |
id | pubmed-6135156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-61351562018-09-24 The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium Trojano, Giuseppe Damiani, Gianluca Raffaello Casavola, Vita Caroli Loiacono, Rossella Malvasi, Antonio Pellegrino, Antonio Siciliano, Valeria Cicinelli, Ettore Salerno, Maria Giovanna Battini, Lorella Gynecol Minim Invasive Ther Original Article BACKGROUNDS AND AIMS: This study aims to compare hysteroscopic and histological findings in asymptomatic postmenopausal patients with thickened endometrium. MATERIALS AND METHODS: A retrospective study involving case records of 295 asymptomatic postmenopausal women with a thickened endometrium >5 mm diagnosed at transvaginal ultrasound (TVS). Patients (women) underwent hysteroscopy with biopsy between 2009 and 2015, and they were followed up at National Cancer Institute of Bari and at University Hospital of Pisa. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of hysteroscopy were evaluated. RESULTS: Inclusion criteria were TVS, hysteroscopy, and endometrial biopsy. When the hysteroscopic findings were normal, a sensitivity of 100%, specificity of 98.6%, PPV of 95.2%, and NPV of 100% were achieved. For polyps and myomas, we found 100%, 98.7%, 99.5%, and 100%, respectively. In case of endometrial hyperplasia, a sensitivity of 66.7%, a specificity of 100%, a PPV of 100%, and a NPV of 98.1% were achieved. For endometrial cancer hysteroscopy, sensitivity, specificity, PPV, and NPV were 100%, 99.6%, 75%, and 100%, respectively. CONCLUSIONS: Hysteroscopy allows an accurate diagnosis in benign endometrial pathology and suspect of malignant endometrial pathology in postmenopausal women with thickened endometrium. Medknow Publications & Media Pvt Ltd 2018 2018-02-16 /pmc/articles/PMC6135156/ /pubmed/30254927 http://dx.doi.org/10.4103/GMIT.GMIT_10_17 Text en Copyright: © 2018 Gynecology and Minimally Invasive Therapy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Trojano, Giuseppe Damiani, Gianluca Raffaello Casavola, Vita Caroli Loiacono, Rossella Malvasi, Antonio Pellegrino, Antonio Siciliano, Valeria Cicinelli, Ettore Salerno, Maria Giovanna Battini, Lorella The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title | The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title_full | The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title_fullStr | The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title_full_unstemmed | The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title_short | The Role of Hysteroscopy in Evaluating Postmenopausal Asymptomatic Women with Thickened Endometrium |
title_sort | role of hysteroscopy in evaluating postmenopausal asymptomatic women with thickened endometrium |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135156/ https://www.ncbi.nlm.nih.gov/pubmed/30254927 http://dx.doi.org/10.4103/GMIT.GMIT_10_17 |
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