Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy

We report cases of two sisters with complete androgen insensitivity syndrome (CAIS). A complete female appearance, blind-ending vagina, and testes in the pelvis are characteristics of CAIS. Prophylactic laparoscopic gonadectomy was performed in both cases. Anti-Müllerian hormone (AMH) level is known...

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Autores principales: Kusumi, Maki, Mitsunami, Makiko, Onoue, Hiroki, Noma, Momo, Matsumura, Fumiko, Tabata, Chisa, Tanaka, Seiji, Watanabe, Noriko, Kurosawa, Takako, Fujiwara, Toshihiro, Tsutusmi, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135182/
https://www.ncbi.nlm.nih.gov/pubmed/30254896
http://dx.doi.org/10.1016/j.gmit.2016.11.001
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author Kusumi, Maki
Mitsunami, Makiko
Onoue, Hiroki
Noma, Momo
Matsumura, Fumiko
Tabata, Chisa
Tanaka, Seiji
Watanabe, Noriko
Kurosawa, Takako
Fujiwara, Toshihiro
Tsutusmi, Osamu
author_facet Kusumi, Maki
Mitsunami, Makiko
Onoue, Hiroki
Noma, Momo
Matsumura, Fumiko
Tabata, Chisa
Tanaka, Seiji
Watanabe, Noriko
Kurosawa, Takako
Fujiwara, Toshihiro
Tsutusmi, Osamu
author_sort Kusumi, Maki
collection PubMed
description We report cases of two sisters with complete androgen insensitivity syndrome (CAIS). A complete female appearance, blind-ending vagina, and testes in the pelvis are characteristics of CAIS. Prophylactic laparoscopic gonadectomy was performed in both cases. Anti-Müllerian hormone (AMH) level is known to be very high in patients with CAIS; AMH is secreted by Sertoli cells and testosterone suppresses the secretion. In our cases, serum AMH was very high before gonadectomy and dramatically decreased after gonadectomy. AMH could be the diagnostic feature for patients with CAIS.
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spelling pubmed-61351822018-09-24 Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy Kusumi, Maki Mitsunami, Makiko Onoue, Hiroki Noma, Momo Matsumura, Fumiko Tabata, Chisa Tanaka, Seiji Watanabe, Noriko Kurosawa, Takako Fujiwara, Toshihiro Tsutusmi, Osamu Gynecol Minim Invasive Ther Case Report We report cases of two sisters with complete androgen insensitivity syndrome (CAIS). A complete female appearance, blind-ending vagina, and testes in the pelvis are characteristics of CAIS. Prophylactic laparoscopic gonadectomy was performed in both cases. Anti-Müllerian hormone (AMH) level is known to be very high in patients with CAIS; AMH is secreted by Sertoli cells and testosterone suppresses the secretion. In our cases, serum AMH was very high before gonadectomy and dramatically decreased after gonadectomy. AMH could be the diagnostic feature for patients with CAIS. Medknow Publications & Media Pvt Ltd 2017 2016-12-10 /pmc/articles/PMC6135182/ /pubmed/30254896 http://dx.doi.org/10.1016/j.gmit.2016.11.001 Text en Copyright: © 2016, The Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kusumi, Maki
Mitsunami, Makiko
Onoue, Hiroki
Noma, Momo
Matsumura, Fumiko
Tabata, Chisa
Tanaka, Seiji
Watanabe, Noriko
Kurosawa, Takako
Fujiwara, Toshihiro
Tsutusmi, Osamu
Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title_full Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title_fullStr Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title_full_unstemmed Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title_short Complete androgen insensitivity syndrome and anti-Müllerian hormone levels before and after laparoscopic gonadectomy
title_sort complete androgen insensitivity syndrome and anti-müllerian hormone levels before and after laparoscopic gonadectomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135182/
https://www.ncbi.nlm.nih.gov/pubmed/30254896
http://dx.doi.org/10.1016/j.gmit.2016.11.001
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