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Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy

BACKGROUND: Effective gastric carcinoma (GC) chemotherapy is subject to many in vitro and in vivo barriers, such as tumor microenvironment and multidrug resistance. MATERIALS AND METHODS: Herein, we developed a hyaluronic acid (HA)-modified silica nanoparticle (HA-SiLN/QD) co-delivering quercetin an...

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Detalles Bibliográficos
Autores principales: Fang, Jian, Zhang, Shangwu, Xue, Xiaofeng, Zhu, Xinguo, Song, Shiduo, Wang, Bin, Jiang, Linhua, Qin, Mingde, Liang, Hansi, Gao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135215/
https://www.ncbi.nlm.nih.gov/pubmed/30233175
http://dx.doi.org/10.2147/IJN.S170862