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Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy
Integrating functional and molecular levels, we investigated the effects of maternal treatment with a xanthine oxidase inhibitor on the programming of cardiac dysfunction in adult offspring using an established rat model of hypoxic pregnancy. Female Wistar rats were divided into normoxic or hypoxic...
Autores principales: | Niu, Youguo, Kane, Andrew D., Lusby, Ciara M., Allison, Beth J., Chua, Yi Yi, Kaandorp, Joepe J., Nevin-Dolan, Rhiannon, Ashmore, Thomas J., Blackmore, Heather L., Derks, Jan B., Ozanne, Susan E., Giussani, Dino A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott, Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135482/ https://www.ncbi.nlm.nih.gov/pubmed/30354714 http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11363 |
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