Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes

Rab2 is a conserved Rab GTPase with a well-established role in secretory pathway function and phagocytosis. Here we demonstrate that Drosophila Rab2 is recruited to late endosomal membranes, where it controls the fusion of LAMP-containing biosynthetic carriers and lysosomes to late endosomes. In con...

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Detalles Bibliográficos
Autores principales: Lund, Viktor Karlovich, Madsen, Kenneth Lindegaard, Kjaerulff, Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135592/
https://www.ncbi.nlm.nih.gov/pubmed/29940804
http://dx.doi.org/10.1080/15548627.2018.1458170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135592/
https://www.ncbi.nlm.nih.gov/pubmed/29940804
http://dx.doi.org/10.1080/15548627.2018.1458170

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