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Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes
Rab2 is a conserved Rab GTPase with a well-established role in secretory pathway function and phagocytosis. Here we demonstrate that Drosophila Rab2 is recruited to late endosomal membranes, where it controls the fusion of LAMP-containing biosynthetic carriers and lysosomes to late endosomes. In con...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135592/ https://www.ncbi.nlm.nih.gov/pubmed/29940804 http://dx.doi.org/10.1080/15548627.2018.1458170 |