Chromatin remodeling protein HELLS is upregulated by inactivation of the RB-E2F pathway and is nonessential for osteosarcoma tumorigenesis

Osteosarcoma is the most common primary bone malignancy in children and adolescents. Among the various molecular mechanisms implicated in osteosarcomagenesis, the RB-E2F pathway is of particular importance as virtually all cases of osteosarcoma display alterations in the RB-E2F pathway. In this stud...

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Detalles Bibliográficos
Autores principales: Wu, Stephanie C., Benavente, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135688/
https://www.ncbi.nlm.nih.gov/pubmed/30220967
http://dx.doi.org/10.18632/oncotarget.25953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135688/
https://www.ncbi.nlm.nih.gov/pubmed/30220967
http://dx.doi.org/10.18632/oncotarget.25953

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