Cargando…

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

PURPOSE: We evaluated longitudinal tracking of BRAF V600E in circulating cell-free DNA (cfDNA) as a marker of treatment response to BRAF inhibitor (BRAFi) combination therapies in non-melanoma solid tumors included in the Copenhagen Prospective Personalized Oncology (CoPPO) program. EXPERIMENTAL DES...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahlborn, Lise Barlebo, Tuxen, Ida Viller, Mouliere, Florent, Kinalis, Savvas, Schmidt, Ane Y., Rohrberg, Kristoffer Staal, Santoni-Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik, Yde, Christina Westmose, Oestrup, Olga, Mau-Sorensen, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135692/ https://www.ncbi.nlm.nih.gov/pubmed/30220966 http://dx.doi.org/10.18632/oncotarget.25948

Ejemplares similares

Plasma total cell-free DNA is a prognostic biomarker of overall survival in metastatic solid tumour patients
por: Viller Tuxen, Ida, et al.
Publicado: (2019)

High frequency of pathogenic germline variants within homologous recombination repair in patients with advanced cancer
por: Bertelsen, Birgitte, et al.
Publicado: (2019)

Application of cell-free DNA for genomic tumor profiling: a feasibility study
por: Ahlborn, Lise B., et al.
Publicado: (2019)

Detection of copy number alterations in cell-free tumor DNA from plasma
por: Østrup, Olga, et al.
Publicado: (2017)

A phase II study of daily encorafenib in combination with biweekly cetuximab in patients with BRAF V600E mutated metastatic colorectal cancer: the NEW BEACON study
por: Eriksen, Martina, et al.
Publicado: (2022)

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study
por: Nørøxe, Dorte Schou, et al.
Publicado: (2019)

ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling – a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial
por: Kringelbach, Tina, et al.
Publicado: (2023)

Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma: a prospective study
por: Schou Nørøxe, Dorte, et al.
Publicado: (2021)

Deconvolution of autoencoders to learn biological regulatory modules from single cell mRNA sequencing data
por: Kinalis, Savvas, et al.
Publicado: (2019)

Actionable Molecular Alterations Are Revealed in Majority of Advanced Non-Small Cell Lung Cancer Patients by Genomic Tumor Profiling at Progression after First Line Treatment
por: Frank, Malene Støchkel, et al.
Publicado: (2021)

Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy
por: Borch, Annie, et al.
Publicado: (2023)

Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study
por: Nørøxe, Dorte S., et al.
Publicado: (2020)

Detection of circulating tumor-derived material in peripheral blood of pediatric sarcoma patients: A systematic review
por: Kjær, Eva Kristine Ruud, et al.
Publicado: (2023)

Interpretable Autoencoders Trained on Single Cell Sequencing Data Can Transfer Directly to Data from Unseen Tissues
por: Walbech, Julie Sparholt, et al.
Publicado: (2021)

Maternal versus paternal inheritance of a 132 bp 11p15.5 microdeletion affecting KCNQ1OT1 and associated phenotypes
por: Stoltze, Ulrik Kristoffer, et al.
Publicado: (2023)

Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types
por: Araujo B. de Lima, Vinicius, et al.
Publicado: (2021)

A Comparison of Tools for Copy-Number Variation Detection in Germline Whole Exome and Whole Genome Sequencing Data
por: Gabrielaite, Migle, et al.
Publicado: (2021)

A catalog of curated breast cancer genes
por: Bose, Muthiah, et al.
Publicado: (2021)

Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors
por: Park, Charny, et al.
Publicado: (2015)

Tissue-Agnostic Activity of BRAF plus MEK Inhibitor in BRAF V600–Mutant Tumors
por: Adashek, Jacob J., et al.
Publicado: (2022)

Application of whole‐exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia
por: Leinøe, Eva, et al.
Publicado: (2017)

Blood-Based Detection of BRAF V600E in Gliomas and Brain Tumor Metastasis
por: Kang, Keiko M., et al.
Publicado: (2021)

BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles
por: Bagger, Frederik Otzen, et al.
Publicado: (2019)

Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade
por: Nazerai, Loulieta, et al.
Publicado: (2022)

Deep targeted sequencing of TP53 in chronic lymphocytic leukemia: clinical impact at diagnosis and at time of treatment
por: Brieghel, Christian, et al.
Publicado: (2019)

Intra- and Inter-Tumor Heterogeneity of BRAF(V600E)Mutations in Primary and Metastatic Melanoma
por: Yancovitz, Molly, et al.
Publicado: (2012)

Survival According to BRAF-V600 Tumor Mutations – An Analysis of 437 Patients with Primary Melanoma
por: Meckbach, Diana, et al.
Publicado: (2014)

Using BRAF(V600E) as a marker of autophagy dependence in pediatric brain tumors
por: Levy, Jean M Mulcahy, et al.
Publicado: (2014)

BRAF‐V600E immunohistochemistry in a large series of glial and glial–neuronal tumors
por: Breton, Quentin, et al.
Publicado: (2017)

Tissue architecture delineates field cancerization in BRAF(V600E)-induced tumor development
por: Schoultz, Elin, et al.
Publicado: (2021)

Comparative BRAF V600E immunohistochemical expression in differentiated thyroid tumors with papillary features
por: Wahid, Maha Hatem Abdul, et al.
Publicado: (2022)

La participación estudiantil en el proceso de aprendizaje
por: Santoni Rugiu, Antonio
Publicado: (1978)

Historia social de la educación /
por: Santoni Rugiu, Antonio
Publicado: (1981)

Nostalgia del maestro artesano
por: Santoni Rugiu, Antonio
Publicado: (1996)

Nostalgia del maestro artesano
por: Santoni Rugiu, Antonio
Publicado: (1994)

Lkb1 Loss Promotes Tumor Progression of BRAF(V600E)-Induced Lung Adenomas
por: González-Sánchez, Elena, et al.
Publicado: (2013)

The Homeobox Gene MEIS1 Is Methylated in BRAF (p.V600E) Mutated Colon Tumors
por: Dihal, Ashwin A., et al.
Publicado: (2013)

BRAF V600E Detection in Liquid Biopsies from Pediatric Central Nervous System Tumors
por: García-Romero, Noemi, et al.
Publicado: (2019)

Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis
por: Togni, Lucrezia, et al.
Publicado: (2022)

Dual inhibition of BRAF and mTOR in BRAF(V600E)-mutant pediatric, adolescent, and young adult brain tumors
por: Sen, Shiraj, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dtk3vukavnrs91b2cl44fpghpb