Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer

Muscle invasive bladder cancer (MIBC) is a common malignancy and major cause of morbidity worldwide. Over the last decade mortality rates for MIBC have not decreased as compared to other cancers indicating a need for novel strategies. The molecular chaperones HSP70 and HSP90 fold and maintain the 3-...

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Detalles Bibliográficos
Autores principales: Prince, Thomas, Ackerman, Andrew, Cavanaugh, Alice, Schreiter, Brielle, Juengst, Brendon, Andolino, Chaylen, Danella, John, Chernin, Mitch, Williams, Heinric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135696/
https://www.ncbi.nlm.nih.gov/pubmed/30220976
http://dx.doi.org/10.18632/oncotarget.26021

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