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In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example

Cancer stem cell (CSC) identification relies on transplantation assays of cell subpopulations sorted from fresh tumor samples. Here, we attempt to bypass limitations of abundant tumor source and predetermined immune selection by in vivo propagating patient-derived xenografts (PDX) from human maligna...

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Detalles Bibliográficos
Autores principales: Golan, Hana, Shukrun, Rachel, Caspi, Revital, Vax, Einav, Pode-Shakked, Naomi, Goldberg, Sanja, Pleniceanu, Oren, Bar-Lev, Dekel D., Mark-Danieli, Michal, Pri-Chen, Sara, Jacob-Hirsch, Jasmine, Kanter, Itamar, Trink, Ariel, Schiby, Ginette, Bilik, Ron, Kalisky, Tomer, Harari-Steinberg, Orit, Toren, Amos, Dekel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135722/
https://www.ncbi.nlm.nih.gov/pubmed/30122444
http://dx.doi.org/10.1016/j.stemcr.2018.07.010