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In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example
Cancer stem cell (CSC) identification relies on transplantation assays of cell subpopulations sorted from fresh tumor samples. Here, we attempt to bypass limitations of abundant tumor source and predetermined immune selection by in vivo propagating patient-derived xenografts (PDX) from human maligna...
Autores principales: | Golan, Hana, Shukrun, Rachel, Caspi, Revital, Vax, Einav, Pode-Shakked, Naomi, Goldberg, Sanja, Pleniceanu, Oren, Bar-Lev, Dekel D., Mark-Danieli, Michal, Pri-Chen, Sara, Jacob-Hirsch, Jasmine, Kanter, Itamar, Trink, Ariel, Schiby, Ginette, Bilik, Ron, Kalisky, Tomer, Harari-Steinberg, Orit, Toren, Amos, Dekel, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135722/ https://www.ncbi.nlm.nih.gov/pubmed/30122444 http://dx.doi.org/10.1016/j.stemcr.2018.07.010 |
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