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The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation
The development of midbrain dopaminergic (mDA) neurons is controlled by multiple morphogens and transcription factors. However, little is known about the role of extracellular matrix proteins in this process. Here we examined the function of roof plate-specific spondins (RSPO1-4) and the floor plate...
Autores principales: | Gyllborg, Daniel, Ahmed, Maqsood, Toledo, Enrique M., Theofilopoulos, Spyridon, Yang, Shanzheng, ffrench-Constant, Charles, Arenas, Ernest |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135723/ https://www.ncbi.nlm.nih.gov/pubmed/30146491 http://dx.doi.org/10.1016/j.stemcr.2018.07.014 |
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