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Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses
Seven human isoforms of importin α mediate nuclear import of cargo in a tissue- and isoform-specific manner. How nuclear import adaptors differentially interact with cargo harbouring the same nuclear localisation signal (NLS) remains poorly understood, as the NLS recognition region is highly conserv...
Autores principales: | Smith, Kate M., Tsimbalyuk, Sofiya, Edwards, Megan R., Cross, Emily M., Batra, Jyoti, Soares da Costa, Tatiana P., Aragão, David, Basler, Christopher F., Forwood, Jade K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135763/ https://www.ncbi.nlm.nih.gov/pubmed/30209309 http://dx.doi.org/10.1038/s41467-018-05928-5 |
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