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PARP-1-dependent RND1 transcription induced by topoisomerase I cleavage complexes confers cellular resistance to camptothecin
RHO GTPases regulate essential functions such as the organization of the actin cytoskeleton. The classic members cycle between an active GTP-bound and an inactive GDP-bound conformation whereas atypical members are predominantly GTP-bound. Besides their well-established role, the classic RHO GTPases...
Autores principales: | Mouly, Laetitia, Mamouni, Kenza, Gence, Remi, Cristini, Agnese, Cherier, Julia, Castinel, Adrien, Legrand, Morgane, Favre, Gilles, Sordet, Olivier, Monferran, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135836/ https://www.ncbi.nlm.nih.gov/pubmed/30209297 http://dx.doi.org/10.1038/s41419-018-0981-3 |
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