Cargando…

A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs

Differentiation of human pluripotent stem cells (hPSCs) into striatal medium spiny neurons (MSNs) promises a cell-based therapy for Huntington's disease. However, clinical-grade MSNs remain unavailable. Here, we developed a chemical recipe named XLSBA to generate clinical-grade MSNs from embryo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Menghua, Zhang, Da, Bi, Chunying, Mi, Tingwei, Zhu, Wenliang, Xia, Longkuo, Teng, Zhaoqian, Hu, Baoyang, Wu, Yihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135866/ https://www.ncbi.nlm.nih.gov/pubmed/30174316 http://dx.doi.org/10.1016/j.stemcr.2018.08.005

Ejemplares similares

hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts
por: Todorova, Dilyana, et al.
Publicado: (2020)

Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies
por: Ji, Tian‐Tian, et al.
Publicado: (2023)

First case of COVID‐19 infused with hESC derived immunity‐ and matrix‐regulatory cells
por: Wu, Jun, et al.
Publicado: (2020)

Quantification of the morphological characteristics of hESC colonies
por: Orozco-Fuentes, Sirio, et al.
Publicado: (2019)

Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome
por: Zhu, Wenliang, et al.
Publicado: (2019)

Phase 1 trial for treatment of COVID‐19 patients with pulmonary fibrosis using hESC‐IMRCs
por: Wu, Jun, et al.
Publicado: (2020)

Generation of Myospheres From hESCs by Epigenetic Reprogramming
por: Albini, Sonia, et al.
Publicado: (2014)

Seeding hESCs to achieve optimal colony clonality
por: Wadkin, L. E., et al.
Publicado: (2019)

hESC Expansion and Stemness Are Independent of Connexin Forty-Three-Mediated Intercellular Communication between hESCs and hASC Feeder Cells
por: Kim, Jin-Su, et al.
Publicado: (2013)

Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs
por: Liang, Lingmin, et al.
Publicado: (2022)

A Teratocarcinoma-Like Human Embryonic Stem Cell (hESC) Line and Four hESC Lines Reveal Potentially Oncogenic Genomic Changes
por: Hovatta, Outi, et al.
Publicado: (2010)

Infusion of hESC derived Immunity‐and‐matrix regulatory cells improves cognitive ability in early‐stage AD mice
por: Liu, Jing, et al.
Publicado: (2021)

Demarcation of Stable Subpopulations within the Pluripotent hESC Compartment
por: Bhatia, Sonam, et al.
Publicado: (2013)

c-JUN is a barrier in hESC to cardiomyocyte transition
por: Zhong, Hui, et al.
Publicado: (2023)

Strategy for the creation of clinical grade hESC line banks that HLA-match a target population
por: Jacquet, Laureen, et al.
Publicado: (2013)

DeephESC 2.0: Deep Generative Multi Adversarial Networks for improving the classification of hESC
por: Theagarajan, Rajkumar, et al.
Publicado: (2019)

Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation
por: McGill, Trevor J., et al.
Publicado: (2017)

Early Acquisition of Neural Crest Competence During hESCs Neuralization
por: Curchoe, Carol Lynn, et al.
Publicado: (2010)

Stabilization of hESCs in two distinct substates along the continuum of pluripotency
por: Dekel, Chen, et al.
Publicado: (2022)

hESC‐Derived Epicardial Cells Promote Repair of Infarcted Hearts in Mouse and Swine
por: Luo, Xiao‐Ling, et al.
Publicado: (2023)

Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines
por: Liu, Ying, et al.
Publicado: (2006)

hESCs‐Derived Early Vascular Cell Spheroids for Cardiac Tissue Vascular Engineering and Myocardial Infarction Treatment
por: Liu, Yang, et al.
Publicado: (2022)

hESC-Derived Cardiomyocytes Electrically Couple and Suppress Arrhythmias in Injured Hearts
por: Shiba, Yuji, et al.
Publicado: (2012)

Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis
por: Yousef, Hanadie, et al.
Publicado: (2014)

Transplantation of hESC-derived hepatocytes protects mice from liver injury
por: Tolosa, Laia, et al.
Publicado: (2015)

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes
por: Cameron, Kate, et al.
Publicado: (2015)

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors
por: Krentz, Nicole A.J., et al.
Publicado: (2018)

Polysome profiling followed by RNA-seq of cardiac differentiation stages in hESCs
por: Pereira, Isabela Tiemy, et al.
Publicado: (2018)

Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies
por: Ali, Muhammad, et al.
Publicado: (2019)

The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis
por: Griffiths, Rosie, et al.
Publicado: (2020)

Cell maturation influences the ability of hESC-RPE to tolerate cellular stress
por: Viheriälä, Taina, et al.
Publicado: (2022)

KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs
por: Xu, Ya-Jie, et al.
Publicado: (2022)

Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation
por: Wang, Jiawen, et al.
Publicado: (2019)

Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD
por: Kriks, Sonja, et al.
Publicado: (2011)

A multi-omics approach to visualize early neuronal differentiation from hESCs in 4D
por: Samara, Athina, et al.
Publicado: (2022)

Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol
por: Spildrejorde, Mari, et al.
Publicado: (2023)

From MEFs to Matrigel 3: Passaging hESCs from Matrigel onto Matrigel
por: Zhang, Jin, et al.
Publicado: (2008)

Specific Marking of hESCs-Derived Hematopoietic Lineage by WAS-Promoter Driven Lentiviral Vectors
por: Muñoz, Pilar, et al.
Publicado: (2012)

hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding
por: Yousef, Hanadie, et al.
Publicado: (2013)

hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
por: Heuer, Andreas, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_pnkfhtuh9fg6s5fauftn816ve4