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Rapid Turnover of the Cardiac L-Type Ca(V)1.2 Channel by Endocytic Recycling Regulates Its Cell Surface Availability
Calcium entry through Ca(V)1.2 L-type calcium channels regulates cardiac contractility. Here, we study the impact of exocytic and post-endocytic trafficking on cell surface channel abundance in cardiomyocytes. Single-molecule localization and confocal microscopy reveal an intracellular Ca(V)1.2 pool...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135870/ https://www.ncbi.nlm.nih.gov/pubmed/30267672 http://dx.doi.org/10.1016/j.isci.2018.08.012 |