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Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions
The human intestinal mucosa is a critical site for absorption, distribution, metabolism, and excretion (ADME)/Tox studies in drug development and is difficult to recapitulate in vitro. Using bioprinting, we generated three-dimensional (3D) intestinal tissue composed of human primary intestinal epith...
Autores principales: | Madden, Lauran R., Nguyen, Theresa V., Garcia-Mojica, Salvador, Shah, Vishal, Le, Alex V., Peier, Andrea, Visconti, Richard, Parker, Eric M., Presnell, Sharon C., Nguyen, Deborah G., Retting, Kelsey N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135981/ https://www.ncbi.nlm.nih.gov/pubmed/30428372 http://dx.doi.org/10.1016/j.isci.2018.03.015 |
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