The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

Our hypothesis is that changes in gene and protein expression are crucial to the development of late-onset Alzheimer’s disease. Previously we examined how DNA alleles control downstream expression of RNA transcripts and how those relationships are changed in late-onset Alzheimer’...

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Detalles Bibliográficos
Autores principales: Petyuk, Vladislav A, Chang, Rui, Ramirez-Restrepo, Manuel, Beckmann, Noam D, Henrion, Marc Y R, Piehowski, Paul D, Zhu, Kuixi, Wang, Sven, Clarke, Jennifer, Huentelman, Matthew J, Xie, Fang, Andreev, Victor, Engel, Anzhelika, Guettoche, Toumy, Navarro, Loida, De Jager, Philip, Schneider, Julie A, Morris, Christopher M, McKeith, Ian G, Perry, Robert H, Lovestone, Simon, Woltjer, Randall L, Beach, Thomas G, Sue, Lucia I, Serrano, Geidy E, Lieberman, Andrew P, Albin, Roger L, Ferrer, Isidre, Mash, Deborah C, Hulette, Christine M, Ervin, John F, Reiman, Eric M, Hardy, John A, Bennett, David A, Schadt, Eric, Smith, Richard D, Myers, Amanda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136080/
https://www.ncbi.nlm.nih.gov/pubmed/30137212
http://dx.doi.org/10.1093/brain/awy215

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