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Preventing coronary artery lesions in Kawasaki disease [Image: see text]
A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has inc...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Chang Gung University
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136281/ https://www.ncbi.nlm.nih.gov/pubmed/28651735 http://dx.doi.org/10.1016/j.bj.2017.04.002 |
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author | Kuo, Ho-Chang |
author_facet | Kuo, Ho-Chang |
author_sort | Kuo, Ho-Chang |
collection | PubMed |
description | A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has increased over recent decades in many centuries, including Japan, Korea, and China. The most severe complications of KD are coronary artery lesions (CAL), including dilation, fistula, aneurysm, arterial remodeling, stenosis, and occlusion. Aneurysm formation has been observed in 20–25% of KD patients that do not receive intravenous immunoglobulin (IVIG) treatment, and in 3–5% that do receive it. Coronary artery dilation has been found in about 30% of KD patients in the acute stage, although mostly in the transient form. Diminishing the occurrence and regression of CAL is a vital part of treating KD. In this review article, I demonstrate the clinical method to prevent CAL formation used at the Kawasaki Disease Center in Taiwan. |
format | Online Article Text |
id | pubmed-6136281 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Chang Gung University |
record_format | MEDLINE/PubMed |
spelling | pubmed-61362812018-09-27 Preventing coronary artery lesions in Kawasaki disease [Image: see text] Kuo, Ho-Chang Biomed J Review Article A form of systemic vasculitis that affects mostly small and medium-sized vessels, Kawasaki disease (KD) is most commonly found in children under the age of 5 years old. Though its etiology is unknown, KD has been the most frequent acquired heart disease in developing countries. Its incidence has increased over recent decades in many centuries, including Japan, Korea, and China. The most severe complications of KD are coronary artery lesions (CAL), including dilation, fistula, aneurysm, arterial remodeling, stenosis, and occlusion. Aneurysm formation has been observed in 20–25% of KD patients that do not receive intravenous immunoglobulin (IVIG) treatment, and in 3–5% that do receive it. Coronary artery dilation has been found in about 30% of KD patients in the acute stage, although mostly in the transient form. Diminishing the occurrence and regression of CAL is a vital part of treating KD. In this review article, I demonstrate the clinical method to prevent CAL formation used at the Kawasaki Disease Center in Taiwan. Chang Gung University 2017-06 2017-05-30 /pmc/articles/PMC6136281/ /pubmed/28651735 http://dx.doi.org/10.1016/j.bj.2017.04.002 Text en © 2017 Chang Gung University. Publishing services by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Kuo, Ho-Chang Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title | Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title_full | Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title_fullStr | Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title_full_unstemmed | Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title_short | Preventing coronary artery lesions in Kawasaki disease [Image: see text] |
title_sort | preventing coronary artery lesions in kawasaki disease [image: see text] |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136281/ https://www.ncbi.nlm.nih.gov/pubmed/28651735 http://dx.doi.org/10.1016/j.bj.2017.04.002 |
work_keys_str_mv | AT kuohochang preventingcoronaryarterylesionsinkawasakidiseaseimageseetext |