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Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene

Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis of a variety of diseases including atheroscler...

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Detalles Bibliográficos
Autores principales:	Idrees, Muhammad, Siddiq, Abdul Rauf, Ajmal, Muhammad, Akram, Muhammad, Khalid, Rana Rehan, Hussain, Alamdar, Qamar, Raheel, Bokhari, Habib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2018
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136370/ https://www.ncbi.nlm.nih.gov/pubmed/30044465 http://dx.doi.org/10.1590/1678-4685-GMB-2016-0287

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