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High glucose induces a priming effect in macrophages and exacerbates the production of pro-inflammatory cytokines after a challenge

INTRODUCTION: Painful diabetic neuropathy is associated with chronic inflammation, in which macrophages are the key effectors. We utilized an in vitro approach to determine the effects of high glucose on macrophage phenotype. MATERIALS AND METHODS: We exposed human THP-1 macrophages to normal glucos...

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Detalles Bibliográficos
Autores principales:	Grosick, Rachel, Alvarado-Vazquez, Perla Abigail, Messersmith, Amy R, Romero-Sandoval, E Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136416/ https://www.ncbi.nlm.nih.gov/pubmed/30237731 http://dx.doi.org/10.2147/JPR.S164493

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