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SIR Model for Dengue Disease with Effect of Dengue Vaccination

The dengue disease is caused by dengue virus, and there is no specific treatment. The medical care by experienced physicians and nurses will save life and will lower the mortality rate. A dengue vaccine to control the disease is available in Thailand since late 2016. A mathematical model would be an...

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Autores principales: Chanprasopchai, Pratchaya, Tang, I. Ming, Pongsumpun, Puntani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136472/
https://www.ncbi.nlm.nih.gov/pubmed/30228830
http://dx.doi.org/10.1155/2018/9861572
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author Chanprasopchai, Pratchaya
Tang, I. Ming
Pongsumpun, Puntani
author_facet Chanprasopchai, Pratchaya
Tang, I. Ming
Pongsumpun, Puntani
author_sort Chanprasopchai, Pratchaya
collection PubMed
description The dengue disease is caused by dengue virus, and there is no specific treatment. The medical care by experienced physicians and nurses will save life and will lower the mortality rate. A dengue vaccine to control the disease is available in Thailand since late 2016. A mathematical model would be an important way to analyze the effects of the vaccination on the transmission of the disease. We have formulated an SIR (susceptible-infected-recovered) model of the transmission of the disease which includes the effect of vaccination and used standard dynamical modelling methods to analyze the effects. The equilibrium states and their stabilities are investigated. The trajectories of the numerical solutions plotted into the 2D planes and 3D spaces are presented. The main contribution is determining the role of dengue vaccination in the model. From the analysis, we find that there is a significant reduction in the total hospitalization time needed to treat the illness.
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spelling pubmed-61364722018-09-18 SIR Model for Dengue Disease with Effect of Dengue Vaccination Chanprasopchai, Pratchaya Tang, I. Ming Pongsumpun, Puntani Comput Math Methods Med Research Article The dengue disease is caused by dengue virus, and there is no specific treatment. The medical care by experienced physicians and nurses will save life and will lower the mortality rate. A dengue vaccine to control the disease is available in Thailand since late 2016. A mathematical model would be an important way to analyze the effects of the vaccination on the transmission of the disease. We have formulated an SIR (susceptible-infected-recovered) model of the transmission of the disease which includes the effect of vaccination and used standard dynamical modelling methods to analyze the effects. The equilibrium states and their stabilities are investigated. The trajectories of the numerical solutions plotted into the 2D planes and 3D spaces are presented. The main contribution is determining the role of dengue vaccination in the model. From the analysis, we find that there is a significant reduction in the total hospitalization time needed to treat the illness. Hindawi 2018-08-28 /pmc/articles/PMC6136472/ /pubmed/30228830 http://dx.doi.org/10.1155/2018/9861572 Text en Copyright © 2018 Pratchaya Chanprasopchai et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chanprasopchai, Pratchaya
Tang, I. Ming
Pongsumpun, Puntani
SIR Model for Dengue Disease with Effect of Dengue Vaccination
title SIR Model for Dengue Disease with Effect of Dengue Vaccination
title_full SIR Model for Dengue Disease with Effect of Dengue Vaccination
title_fullStr SIR Model for Dengue Disease with Effect of Dengue Vaccination
title_full_unstemmed SIR Model for Dengue Disease with Effect of Dengue Vaccination
title_short SIR Model for Dengue Disease with Effect of Dengue Vaccination
title_sort sir model for dengue disease with effect of dengue vaccination
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136472/
https://www.ncbi.nlm.nih.gov/pubmed/30228830
http://dx.doi.org/10.1155/2018/9861572
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