Cargando…

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity

Cadmium (Cd) is a harmful heavy metal, which causes severe brain damage and neurotoxic effects. Polydeoxyribonucleotide (PDRN) stimulates adenosine A(2A) receptor, thus contrasting several deleterious mechanisms in course of tissue damages. We aimed to investigate the possible neuroprotective effect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marini, Herbert R., Puzzolo, Domenico, Micali, Antonio, Adamo, Elena Bianca, Irrera, Natasha, Pisani, Antonina, Pallio, Giovanni, Trichilo, Vincenzo, Malta, Consuelo, Bitto, Alessandra, Squadrito, Francesco, Altavilla, Domenica, Minutoli, Letteria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136506/ https://www.ncbi.nlm.nih.gov/pubmed/30228855 http://dx.doi.org/10.1155/2018/4285694

Ejemplares similares

Corrigendum to “Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity”
por: Marini, Herbert R., et al.
Publicado: (2018)

Polydeoxyribonucleotide, an Adenosine-A2(A) Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury
por: Squadrito, Francesco, et al.
Publicado: (2017)

Corrigendum: Polydeoxyribonucleotide, an adenosine-A2(A) receptor agonist, preserves blood testis barrier from cadmium-induced injury
por: Squadrito, Francesco, et al.
Publicado: (2022)

Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity
por: Micali, Antonio, et al.
Publicado: (2018)

Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity
por: Mannino, Federica, et al.
Publicado: (2021)

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury
por: Minutoli, Letteria, et al.
Publicado: (2016)

Involvement of Hypoxia-Inducible Factor 1-α in Experimental Testicular Ischemia and Reperfusion: Effects of Polydeoxyribonucleotide and Selenium
por: Antonuccio, Pietro, et al.
Publicado: (2022)

Beneficial Effects of Polydeoxyribonucleotide (PDRN) in an In Vitro Model of Fuchs Endothelial Corneal Dystrophy
por: Ceravolo, Ida, et al.
Publicado: (2022)

Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele
por: Minutoli, Letteria, et al.
Publicado: (2015)

Protective Effects of Myo-Inositol and Selenium on Cadmium-Induced Thyroid Toxicity in Mice
por: Benvenga, Salvatore, et al.
Publicado: (2020)

Pharmacological Activity and Clinical Use of PDRN
por: Squadrito, Francesco, et al.
Publicado: (2017)

Corrigendum: Pharmacological activity and clinical use of PDRN
por: Squadrito, Francesco, et al.
Publicado: (2022)

Nutraceutical Effects of Lycopene in Experimental Varicocele: An “In Vivo” Model to Study Male Infertility
por: Antonuccio, Pietro, et al.
Publicado: (2020)

Apoptotic Pathways Linked to Endocrine System as Potential Therapeutic Targets for Benign Prostatic Hyperplasia
por: Minutoli, Letteria, et al.
Publicado: (2016)

Beta-Caryophyllene, a Plant-Derived CB2 Receptor Agonist, Protects SH-SY5Y Cells from Cadmium-Induced Toxicity
por: Mannino, Federica, et al.
Publicado: (2023)

Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis
por: Pallio, Giovanni, et al.
Publicado: (2016)

Survivin and NAIP in Human Benign Prostatic Hyperplasia: Protective Role of the Association of Serenoa repens, Lycopene and Selenium from the Randomized Clinical Study
por: Morgia, Giuseppe, et al.
Publicado: (2017)

Corrigendum: Adenosine receptor stimulation by polydeoxyribonucleotide improves tissue repair and symptomology in experimental colitis
por: Pallio, Giovanni, et al.
Publicado: (2022)

The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury
por: Irrera, Natasha, et al.
Publicado: (2020)

Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing
por: Galeano, Mariarosaria, et al.
Publicado: (2021)

Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents
por: Pizzino, Gabriele, et al.
Publicado: (2017)

Combined Treatment with Polynucleotides and Hyaluronic Acid Improves Tissue Repair in Experimental Colitis
por: Pallio, Giovanni, et al.
Publicado: (2020)

The Association of Myo-Inositol and Selenium Contrasts Cadmium-Induced Thyroid C Cell Hyperplasia and Hypertrophy in Mice
por: Benvenga, Salvatore, et al.
Publicado: (2021)

Cadmium-Induced Kidney Injury in Mice Is Counteracted by a Flavonoid-Rich Extract of Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, via the Enhancement of Different Defense Mechanisms
por: Cirmi, Santa, et al.
Publicado: (2021)

Nutraceuticals as Alternative Approach against Cadmium-Induced Kidney Damage: A Narrative Review
por: Marini, Herbert Ryan, et al.
Publicado: (2023)

Levels of Heavy Metals in Adolescents Living in the Industrialised Area of Milazzo-Valle del Mela (Northern Sicily)
por: Interdonato, Monica, et al.
Publicado: (2014)

MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
por: Pallio, Giovanni, et al.
Publicado: (2021)

PDRN, a Bioactive Natural Compound, Ameliorates Imiquimod-Induced Psoriasis through NF-κB Pathway Inhibition and Wnt/β-Catenin Signaling Modulation
por: Irrera, Natasha, et al.
Publicado: (2020)

Health Potential of Aloe vera against Oxidative Stress Induced Corneal Damage: An “In Vitro” Study
por: Ceravolo, Ida, et al.
Publicado: (2021)

Relaxin improves multiple markers of wound healing and ameliorates the disturbed healing pattern of genetically diabetic mice
por: Bitto, Alessandra, et al.
Publicado: (2013)

Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis
por: Bitto, Alessandra, et al.
Publicado: (2012)

Retraction Note: Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis
por: Bitto, Alessandra, et al.
Publicado: (2023)

Nutraceuticals: A New Challenge against Cadmium-Induced Testicular Injury
por: Marini, Herbert Ryan, et al.
Publicado: (2022)

Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis
por: Pizzino, Gabriele, et al.
Publicado: (2015)

Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells
por: Mannino, Federica, et al.
Publicado: (2021)

Correction: Mannino et al. Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells. Cancers 2021, 13, 5741
por: Mannino, Federica, et al.
Publicado: (2023)

Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy)
por: Pizzino, Gabriele, et al.
Publicado: (2014)

A Flavonoid-Rich Extract from Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, Shows Protective Effects in a Murine Model of Cadmium-Induced Testicular Injury
por: Ferlazzo, Nadia, et al.
Publicado: (2021)

Failure of Achieving Tacrolimus Target Blood Concentration Might Be Avoided by a Wide Genotyping of Transplanted Patients: Evidence from a Retrospective Study
por: Pallio, Giovanni, et al.
Publicado: (2020)

Exploiting Curcumin Synergy With Natural Products Using Quantitative Analysis of Dose–Effect Relationships in an Experimental In Vitro Model of Osteoarthritis
por: D’Ascola, Angela, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kfrrd7f212qdvfc2g8olh5uh1c