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Ocular progenitor cells and current applications in regenerative medicines – Review

The recent emerging field of regenerative medicine is to present solutions for chronic diseases which cannot be sufficiently repaired by the body's own mechanisms. Stem cells are undifferentiated biological cells and have the potential to develop into many different cell types in the body durin...

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Autores principales: Gokuladhas, K., Sivapriya, N., Barath, M., NewComer, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136601/
https://www.ncbi.nlm.nih.gov/pubmed/30258910
http://dx.doi.org/10.1016/j.gendis.2017.01.002
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author Gokuladhas, K.
Sivapriya, N.
Barath, M.
NewComer, Charles H.
author_facet Gokuladhas, K.
Sivapriya, N.
Barath, M.
NewComer, Charles H.
author_sort Gokuladhas, K.
collection PubMed
description The recent emerging field of regenerative medicine is to present solutions for chronic diseases which cannot be sufficiently repaired by the body's own mechanisms. Stem cells are undifferentiated biological cells and have the potential to develop into many different cell types in the body during early life and growth. Self renewal and totipotency are the characteristic features of stem cells and it holds a promising result for treating various diseases like diabetic foot ulcer, heart diseases, lung diseases, Autism, Skin diseases, arthritis including eye disease. Failure of complete recovery of eye diseases and complications that follow conventional treatments have shifted search to a new form of regenerative medicine using Stem cells. The ocular progenitor cells are remarkable in stem cell biology and replenishing degenerated cells despite being present in low quantity and quiescence in our body has a high therapeutic value. In this paper we have review the applications on ocular progenitor stem cells in treatment of human eye diseases and address the strategies that have been exploited in an effort to regain visual function in the advance treatment of stem cells without any side effects and also present the significance in advance stem cell research.
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spelling pubmed-61366012018-09-26 Ocular progenitor cells and current applications in regenerative medicines – Review Gokuladhas, K. Sivapriya, N. Barath, M. NewComer, Charles H. Genes Dis Article The recent emerging field of regenerative medicine is to present solutions for chronic diseases which cannot be sufficiently repaired by the body's own mechanisms. Stem cells are undifferentiated biological cells and have the potential to develop into many different cell types in the body during early life and growth. Self renewal and totipotency are the characteristic features of stem cells and it holds a promising result for treating various diseases like diabetic foot ulcer, heart diseases, lung diseases, Autism, Skin diseases, arthritis including eye disease. Failure of complete recovery of eye diseases and complications that follow conventional treatments have shifted search to a new form of regenerative medicine using Stem cells. The ocular progenitor cells are remarkable in stem cell biology and replenishing degenerated cells despite being present in low quantity and quiescence in our body has a high therapeutic value. In this paper we have review the applications on ocular progenitor stem cells in treatment of human eye diseases and address the strategies that have been exploited in an effort to regain visual function in the advance treatment of stem cells without any side effects and also present the significance in advance stem cell research. Chongqing Medical University 2017-02-10 /pmc/articles/PMC6136601/ /pubmed/30258910 http://dx.doi.org/10.1016/j.gendis.2017.01.002 Text en Copyright © 2017, Chongqing Medical University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Gokuladhas, K.
Sivapriya, N.
Barath, M.
NewComer, Charles H.
Ocular progenitor cells and current applications in regenerative medicines – Review
title Ocular progenitor cells and current applications in regenerative medicines – Review
title_full Ocular progenitor cells and current applications in regenerative medicines – Review
title_fullStr Ocular progenitor cells and current applications in regenerative medicines – Review
title_full_unstemmed Ocular progenitor cells and current applications in regenerative medicines – Review
title_short Ocular progenitor cells and current applications in regenerative medicines – Review
title_sort ocular progenitor cells and current applications in regenerative medicines – review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136601/
https://www.ncbi.nlm.nih.gov/pubmed/30258910
http://dx.doi.org/10.1016/j.gendis.2017.01.002
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