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Characterization of EGF-guided MDA-MB-231 cell chemotaxis in vitro using a physiological and highly sensitive assay system

Chemotactic cell migration is a central mechanism during cancer cell invasion and hence metastasis. In order to mimic in vivo conditions, we used a three-dimensional hydrogel matrix made of collagen I and a stable gradient-generating chemotaxis assay system, which is commercially available (μ-Slide...

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Detalles Bibliográficos
Autores principales:	Biswenger, Verena, Baumann, Nina, Jürschick, Johannes, Häckl, Martina, Battle, Christopher, Schwarz, Jan, Horn, Elias, Zantl, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136702/ https://www.ncbi.nlm.nih.gov/pubmed/30212492 http://dx.doi.org/10.1371/journal.pone.0203040

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