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Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma

BACKGROUND: Esophageal cancer remains one of the hardest cancers to treat with rising incidence rates, low overall survival and high levels of treatment resistance. The lack of clinically available biomarkers hinder diagnosis and treatment stratification. While large scale sequencing approaches have...

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Detalles Bibliográficos
Autores principales: Lohse, Ines, Al-Ali, Hassan, Volmar, Claude-Henry, D. Alvarez Trotta, Annamil, Brothers, Shaun P., Capobianco, Anthony J., Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136712/
https://www.ncbi.nlm.nih.gov/pubmed/30212533
http://dx.doi.org/10.1371/journal.pone.0203173