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Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models

Hepatocellular carcinoma causes ~10% of all cancer-related deaths worldwide, usually emerging in a background of liver fibrosis/cirrhosis (70%-90% of cases). Chemically-induced mouse models for fibrosis-associated hepatocarcinogenesis are widely-applied, resembling the corresponding human disease. N...

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Detalles Bibliográficos
Autores principales: Romualdo, Guilherme Ribeiro, Prata, Gabriel Bacil, da Silva, Tereza Cristina, Fernandes, Ana Angélica Henrique, Moreno, Fernando Salvador, Cogliati, Bruno, Barbisan, Luís Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136798/
https://www.ncbi.nlm.nih.gov/pubmed/30212575
http://dx.doi.org/10.1371/journal.pone.0203879