Cargando…
Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy
Shugoshin-1 (Sgo1) protects the integrity of the centromeres, and H2A phosphorylation is critical for this process. The mitotic checkpoint kinase Bub1, phosphorylates H2A and ensures fidelity of chromosome segregation and chromosome number. Oncogenic KSHV induces genetic alterations through chromoso...
Autores principales: | Lang, Fengchao, Sun, Zhiguo, Pei, Yonggang, Singh, Rajnish Kumar, Jha, Hem Chandra, Robertson, Erle S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136811/ https://www.ncbi.nlm.nih.gov/pubmed/30212568 http://dx.doi.org/10.1371/journal.ppat.1007253 |
Ejemplares similares
-
Correction: Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy
por: Lang, Fengchao, et al.
Publicado: (2019) -
KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation
por: Singh, Rajnish Kumar, et al.
Publicado: (2019) -
KSHV LANA—The Master Regulator of KSHV Latency
por: Uppal, Timsy, et al.
Publicado: (2014) -
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia
por: Singh, Rajnish Kumar, et al.
Publicado: (2018) -
IRF-4-Mediated CIITA Transcription Is Blocked by KSHV Encoded LANA to Inhibit MHC II Presentation
por: Cai, Qiliang, et al.
Publicado: (2013)