SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion

Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-ret...

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Detalles Bibliográficos
Autores principales: McGough, Ian J., de Groot, Reinoud E. A., Jellett, Adam P., Betist, Marco C., Varandas, Katherine C., Danson, Chris M., Heesom, Kate J., Korswagen, Hendrik C., Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137200/
https://www.ncbi.nlm.nih.gov/pubmed/30213940
http://dx.doi.org/10.1038/s41467-018-06114-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137200/
https://www.ncbi.nlm.nih.gov/pubmed/30213940
http://dx.doi.org/10.1038/s41467-018-06114-3

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