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Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study

Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique measuring relative hemodynamic changes in superficial cortical structures. It has successfully been applied to detect a hemodynamic response in the somatosensory cortex evoked by irritating mechanical, electrical, and heat...

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Autores principales: Hucke, Christine I., Pacharra, Marlene, Reinders, Jörg, van Thriel, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137212/
https://www.ncbi.nlm.nih.gov/pubmed/30213998
http://dx.doi.org/10.1038/s41598-018-32147-1
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author Hucke, Christine I.
Pacharra, Marlene
Reinders, Jörg
van Thriel, Christoph
author_facet Hucke, Christine I.
Pacharra, Marlene
Reinders, Jörg
van Thriel, Christoph
author_sort Hucke, Christine I.
collection PubMed
description Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique measuring relative hemodynamic changes in superficial cortical structures. It has successfully been applied to detect a hemodynamic response in the somatosensory cortex evoked by irritating mechanical, electrical, and heat stimulations of limbs or the face. The aim of the current study was to explore the feasibility of fNIRS to detect respective responses evoked by irritating chemical stimulations of the nasal divisions of the trigeminal nerve. In two experiments, healthy subjects were exposed to acetic acid and ethyl acetate presented using a respiration-synchronized olfactometer. Results demonstrated that fNIRS can detect a signal in both hemispheres after birhinal (experiment 1: n = 14) and monorhinal (experiment 2: n = 12) stimulations using acetic acid but not ethyl acetate. This is a first evidence that fNIRS might be a suitable imaging technique to assess chemosensory neuronal correlates in the somatosensory cortex thereby offering a new, portable method to evaluate the irritating properties of certain volatiles in an objective, nonverbal, easy, and comparably inexpensive manner.
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spelling pubmed-61372122018-09-15 Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study Hucke, Christine I. Pacharra, Marlene Reinders, Jörg van Thriel, Christoph Sci Rep Article Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique measuring relative hemodynamic changes in superficial cortical structures. It has successfully been applied to detect a hemodynamic response in the somatosensory cortex evoked by irritating mechanical, electrical, and heat stimulations of limbs or the face. The aim of the current study was to explore the feasibility of fNIRS to detect respective responses evoked by irritating chemical stimulations of the nasal divisions of the trigeminal nerve. In two experiments, healthy subjects were exposed to acetic acid and ethyl acetate presented using a respiration-synchronized olfactometer. Results demonstrated that fNIRS can detect a signal in both hemispheres after birhinal (experiment 1: n = 14) and monorhinal (experiment 2: n = 12) stimulations using acetic acid but not ethyl acetate. This is a first evidence that fNIRS might be a suitable imaging technique to assess chemosensory neuronal correlates in the somatosensory cortex thereby offering a new, portable method to evaluate the irritating properties of certain volatiles in an objective, nonverbal, easy, and comparably inexpensive manner. Nature Publishing Group UK 2018-09-13 /pmc/articles/PMC6137212/ /pubmed/30213998 http://dx.doi.org/10.1038/s41598-018-32147-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hucke, Christine I.
Pacharra, Marlene
Reinders, Jörg
van Thriel, Christoph
Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title_full Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title_fullStr Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title_full_unstemmed Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title_short Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study
title_sort somatosensory response to trigeminal stimulation: a functional near-infrared spectroscopy (fnirs) study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137212/
https://www.ncbi.nlm.nih.gov/pubmed/30213998
http://dx.doi.org/10.1038/s41598-018-32147-1
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