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mTORC1 Negatively Regulates the Replication of Classical Swine Fever Virus Through Autophagy and IRES-Dependent Translation

Classical swine fever virus (CSFV) can utilize diverse host signaling pathways for its replication; however, the cross talk between mammalian target of rapamycin (mTOR) and CSFV remains unknown. Here, we describe the potential role of mTOR complex 1 (mTORC1) in promoting CSFV replication via virus-i...

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Detalles Bibliográficos
Autores principales:	Luo, Qinghua, Zhang, Li, Wei, Feng, Fang, Qiang, Bao, Fei, Mi, Shijiang, Li, Nan, Wang, Chengming, Liu, Yan, Tu, Changchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137324/ https://www.ncbi.nlm.nih.gov/pubmed/30428332 http://dx.doi.org/10.1016/j.isci.2018.04.010

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