Giant cell tumor of a rib following denosumab treatment

Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on compute...

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Detalles Bibliográficos
Autores principales: Semionov, Alexandre, Kosiuk, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Musculoskeletal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137337/
https://www.ncbi.nlm.nih.gov/pubmed/30228835
http://dx.doi.org/10.1016/j.radcr.2018.04.005
Descripción
Sumario:Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab.

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