Giant cell tumor of a rib following denosumab treatment

Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on compute...

Descripción completa

Detalles Bibliográficos
Autores principales: Semionov, Alexandre, Kosiuk, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Musculoskeletal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137337/
https://www.ncbi.nlm.nih.gov/pubmed/30228835
http://dx.doi.org/10.1016/j.radcr.2018.04.005
_version_ 1783355168954253312
author Semionov, Alexandre
Kosiuk, John
author_facet Semionov, Alexandre
Kosiuk, John
author_sort Semionov, Alexandre
collection PubMed
description Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab.
format Online
Article
Text
id pubmed-6137337
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-61373372018-09-18 Giant cell tumor of a rib following denosumab treatment Semionov, Alexandre Kosiuk, John Radiol Case Rep Musculoskeletal Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab. Elsevier 2018-06-01 /pmc/articles/PMC6137337/ /pubmed/30228835 http://dx.doi.org/10.1016/j.radcr.2018.04.005 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Musculoskeletal
Semionov, Alexandre
Kosiuk, John
Giant cell tumor of a rib following denosumab treatment
title Giant cell tumor of a rib following denosumab treatment
title_full Giant cell tumor of a rib following denosumab treatment
title_fullStr Giant cell tumor of a rib following denosumab treatment
title_full_unstemmed Giant cell tumor of a rib following denosumab treatment
title_short Giant cell tumor of a rib following denosumab treatment
title_sort giant cell tumor of a rib following denosumab treatment
topic Musculoskeletal
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137337/
https://www.ncbi.nlm.nih.gov/pubmed/30228835
http://dx.doi.org/10.1016/j.radcr.2018.04.005
work_keys_str_mv AT semionovalexandre giantcelltumorofaribfollowingdenosumabtreatment
AT kosiukjohn giantcelltumorofaribfollowingdenosumabtreatment

Ejemplares similares