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ARAP1 Bridges Actin Dynamics and AP-3-Dependent Membrane Traffic in Bone-Digesting Osteoclasts

Bone-resorbing osteoclasts play a central role in bone remodeling and its pathology. To digest bone, osteoclasts re-organize both F-actin, to assemble podosomes/sealing zones, and membrane traffic, to form bone-facing ruffled borders enriched in lysosomal membrane proteins. It remains elusive how th...

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Detalles Bibliográficos
Autores principales:	Segeletz, Sandra, Danglot, Lydia, Galli, Thierry, Hoflack, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137390/ https://www.ncbi.nlm.nih.gov/pubmed/30240610 http://dx.doi.org/10.1016/j.isci.2018.07.019

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