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Designing novel inhibitors against Mycobacterium tuberculosis FadA5 (acetyl-CoA acetyltransferase) by virtual screening of known anti-tuberculosis (bioactive) compounds

By-products of fatty acid degradation are extensively utilized by Mycobacterium tuberculosis (Mtb) for lipid synthesis and energy production during the infection phase. Cholesterol from host is scavenged by Mtb to fulfill its metabolic requirements, evade host immunity and invade macrophages. Blocki...

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Detalles Bibliográficos
Autores principales:	Jaiswal, Atul Kumar, Husaini, Syed Hussain Abbas, Kumar, Amarjeet, Subbarao, Naidu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2018
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137569/ https://www.ncbi.nlm.nih.gov/pubmed/30237678 http://dx.doi.org/10.6026/97320630014327

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