Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type

Imatinib mesylate, a tyrosine kinase inhibitor, is commonly used in the treatment of chronic myeloid leukemia. IgA pemphigus is a rare bullous dermatosis caused by IgA autoantibodies. Clinical manifestations include localized or generalized itchy blisters and pustules. Drug-induced IgA pemphigus has...

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Autores principales: Sood, Aradhana, Sinha, Preema, Raman, Deep K., Sinha, Anwita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137662/
https://www.ncbi.nlm.nih.gov/pubmed/30258803
http://dx.doi.org/10.4103/idoj.IDOJ_331_17
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author Sood, Aradhana
Sinha, Preema
Raman, Deep K.
Sinha, Anwita
author_facet Sood, Aradhana
Sinha, Preema
Raman, Deep K.
Sinha, Anwita
author_sort Sood, Aradhana
collection PubMed
description Imatinib mesylate, a tyrosine kinase inhibitor, is commonly used in the treatment of chronic myeloid leukemia. IgA pemphigus is a rare bullous dermatosis caused by IgA autoantibodies. Clinical manifestations include localized or generalized itchy blisters and pustules. Drug-induced IgA pemphigus has been rarely reported in the literature till date. Here, we report one such rare case caused by imatinib which responded poorly to oral prednisolone but showed excellent response to tablet dapsone.
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spelling pubmed-61376622018-09-26 Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type Sood, Aradhana Sinha, Preema Raman, Deep K. Sinha, Anwita Indian Dermatol Online J Case Report Imatinib mesylate, a tyrosine kinase inhibitor, is commonly used in the treatment of chronic myeloid leukemia. IgA pemphigus is a rare bullous dermatosis caused by IgA autoantibodies. Clinical manifestations include localized or generalized itchy blisters and pustules. Drug-induced IgA pemphigus has been rarely reported in the literature till date. Here, we report one such rare case caused by imatinib which responded poorly to oral prednisolone but showed excellent response to tablet dapsone. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6137662/ /pubmed/30258803 http://dx.doi.org/10.4103/idoj.IDOJ_331_17 Text en Copyright: © 2018 Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sood, Aradhana
Sinha, Preema
Raman, Deep K.
Sinha, Anwita
Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title_full Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title_fullStr Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title_full_unstemmed Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title_short Imatinib-induced IgA Pemphigus: Subcorneal Pustular Dermatosis Type
title_sort imatinib-induced iga pemphigus: subcorneal pustular dermatosis type
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137662/
https://www.ncbi.nlm.nih.gov/pubmed/30258803
http://dx.doi.org/10.4103/idoj.IDOJ_331_17
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AT sinhaanwita imatinibinducedigapemphigussubcornealpustulardermatosistype

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