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Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma

Paronychia is a painful inflammatory disorder of the nail fold. Periungual pyogenic granuloma – a benign vascular tumor of the capillaries – can develop as a complication of paronychia. We report both, paronychia and periungual pyogenic granuloma, as possible adverse events during systemic drug-ther...

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Autor principal: Wollina, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137670/
https://www.ncbi.nlm.nih.gov/pubmed/30258794
http://dx.doi.org/10.4103/idoj.IDOJ_133_18
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author Wollina, Uwe
author_facet Wollina, Uwe
author_sort Wollina, Uwe
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description Paronychia is a painful inflammatory disorder of the nail fold. Periungual pyogenic granuloma – a benign vascular tumor of the capillaries – can develop as a complication of paronychia. We report both, paronychia and periungual pyogenic granuloma, as possible adverse events during systemic drug-therapy. The following groups of systemic drugs have been considered: taxanes, epidermal growth factor-receptor (EGFR) inhibitors, EGFR tyrosine kinase inhibitors, tyrosine kinase inhibitors, inhibitors of MEK/ERK, BRAF inhibitors, CD20 antagonists, vascular endothelial growth factor inhibitors, and retinoids. Recommendations for prevention and treatment are given. Since paronychia is a painful inflammatory disorder that has a negative impact on daily activities, early recognition and adequate treatment improve adhesion to treatment and quality of life.
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spelling pubmed-61376702018-09-26 Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma Wollina, Uwe Indian Dermatol Online J Review Article Paronychia is a painful inflammatory disorder of the nail fold. Periungual pyogenic granuloma – a benign vascular tumor of the capillaries – can develop as a complication of paronychia. We report both, paronychia and periungual pyogenic granuloma, as possible adverse events during systemic drug-therapy. The following groups of systemic drugs have been considered: taxanes, epidermal growth factor-receptor (EGFR) inhibitors, EGFR tyrosine kinase inhibitors, tyrosine kinase inhibitors, inhibitors of MEK/ERK, BRAF inhibitors, CD20 antagonists, vascular endothelial growth factor inhibitors, and retinoids. Recommendations for prevention and treatment are given. Since paronychia is a painful inflammatory disorder that has a negative impact on daily activities, early recognition and adequate treatment improve adhesion to treatment and quality of life. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6137670/ /pubmed/30258794 http://dx.doi.org/10.4103/idoj.IDOJ_133_18 Text en Copyright: © 2018 Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Wollina, Uwe
Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title_full Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title_fullStr Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title_full_unstemmed Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title_short Systemic Drug-induced Chronic Paronychia and Periungual Pyogenic Granuloma
title_sort systemic drug-induced chronic paronychia and periungual pyogenic granuloma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137670/
https://www.ncbi.nlm.nih.gov/pubmed/30258794
http://dx.doi.org/10.4103/idoj.IDOJ_133_18
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