In silico Prioritization of Transporter–Drug Relationships From Drug Sensitivity Screens

The interplay between drugs and cell metabolism is a key factor in determining both compound potency and toxicity. In particular, how and to what extent transmembrane transporters affect drug uptake and disposition is currently only partially understood. Most transporter proteins belong to two prote...

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Detalles Bibliográficos
Autores principales: César-Razquin, Adrián, Girardi, Enrico, Yang, Mi, Brehme, Marc, Saez-Rodriguez, Julio, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137680/
https://www.ncbi.nlm.nih.gov/pubmed/30245630
http://dx.doi.org/10.3389/fphar.2018.01011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137680/
https://www.ncbi.nlm.nih.gov/pubmed/30245630
http://dx.doi.org/10.3389/fphar.2018.01011

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