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In silico Prioritization of Transporter–Drug Relationships From Drug Sensitivity Screens
The interplay between drugs and cell metabolism is a key factor in determining both compound potency and toxicity. In particular, how and to what extent transmembrane transporters affect drug uptake and disposition is currently only partially understood. Most transporter proteins belong to two prote...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137680/ https://www.ncbi.nlm.nih.gov/pubmed/30245630 http://dx.doi.org/10.3389/fphar.2018.01011 |