Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System

A clustered regularly interspaced short palindromic repeats (CRISPR)-like “mimivirus virophage resistance element” (MIMIVIRE) system, which contains specific cascade genes and a CRISPR array against virophages, was reported in mimiviruses. An essential component of the MIMIVIRE system is R354, encod...

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Detalles Bibliográficos
Autores principales: Dou, Chao, Yu, Mingjing, Gu, Yijun, Wang, Jinjing, Yin, Kun, Nie, Chunlai, Zhu, Xiaofeng, Qi, Shiqian, Wei, Yuquan, Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137704/
https://www.ncbi.nlm.nih.gov/pubmed/30428313
http://dx.doi.org/10.1016/j.isci.2018.04.001

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