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Local Oxidative Damage in the Soma and Dendrites Quarantines Neuronal Mitochondria at the Site of Insult

Neurons are highly dependent on mitochondria, but little is known about how they react to a local mitochondrial oxidative insult. We therefore developed a protocol in primary hippocampal cultures that combines the photosensitizer mito-KillerRed with fluorescent biosensors and photoactivatable GFP. W...

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Detalles Bibliográficos
Autores principales:	Grimm, Amandine, Cummins, Nadia, Götz, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137705/ https://www.ncbi.nlm.nih.gov/pubmed/30240605 http://dx.doi.org/10.1016/j.isci.2018.07.015

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