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Soluble Aβ Oligomers Impair Dipolar Heterodendritic Plasticity by Activation of mGluR in the Hippocampal CA1 Region

Soluble Aβ oligomers (oAβs) contribute importantly to synaptotoxicity in Alzheimer disease (AD), but the mechanisms related to heterogeneity of synaptic functions at local circuits remain elusive. Nearly all studies of the effects of oAβs on hippocampal synaptic plasticity have only examined homosyn...

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Detalles Bibliográficos
Autores principales:	Zhao, Jianhua, Li, Anna, Rajsombath, Molly, Dang, Yifan, Selkoe, Dennis J., Li, Shaomin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137707/ https://www.ncbi.nlm.nih.gov/pubmed/30240608 http://dx.doi.org/10.1016/j.isci.2018.07.018

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