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Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens

BACKGROUND: Pseudocohnilembus persalinus, a unicellular ciliated protozoan, is one of commonest facultative pathogens. We sequenced the macronuclear genome of P. persalinus in 2015, which provided new insights into its pathogenicity. RESULTS: Here, we present the P. persalinus genome database (PPGD)...

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Autores principales: Wei, Wei, Chen, Kai, Miao, Wei, Yang, Wentao, Xiong, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137885/
https://www.ncbi.nlm.nih.gov/pubmed/30217145
http://dx.doi.org/10.1186/s12864-018-5046-6
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author Wei, Wei
Chen, Kai
Miao, Wei
Yang, Wentao
Xiong, Jie
author_facet Wei, Wei
Chen, Kai
Miao, Wei
Yang, Wentao
Xiong, Jie
author_sort Wei, Wei
collection PubMed
description BACKGROUND: Pseudocohnilembus persalinus, a unicellular ciliated protozoan, is one of commonest facultative pathogens. We sequenced the macronuclear genome of P. persalinus in 2015, which provided new insights into its pathogenicity. RESULTS: Here, we present the P. persalinus genome database (PPGD) (http://ciliates.ihb.ac.cn/database/home/#pp), the first genome database for the scuticociliatosis pathogens. PPGD integrates P. persalinus macronuclear genomic and transcriptomic data, including genome sequence, transcript, gene expression data, and gene annotation, as well as relevant information on its biology, morphology and taxonomy. The database also provides functions for visualizing, analyzing, and downloading the data. CONCLUSION: PPGD is a useful resource for studying scuticociliates or scuticociliatosis. We will continue to update the PPGD by integrating more data and aim to integrate the PPGD with other ciliate databases to build a comprehensive ciliate genome database.
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spelling pubmed-61378852018-09-15 Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens Wei, Wei Chen, Kai Miao, Wei Yang, Wentao Xiong, Jie BMC Genomics Database BACKGROUND: Pseudocohnilembus persalinus, a unicellular ciliated protozoan, is one of commonest facultative pathogens. We sequenced the macronuclear genome of P. persalinus in 2015, which provided new insights into its pathogenicity. RESULTS: Here, we present the P. persalinus genome database (PPGD) (http://ciliates.ihb.ac.cn/database/home/#pp), the first genome database for the scuticociliatosis pathogens. PPGD integrates P. persalinus macronuclear genomic and transcriptomic data, including genome sequence, transcript, gene expression data, and gene annotation, as well as relevant information on its biology, morphology and taxonomy. The database also provides functions for visualizing, analyzing, and downloading the data. CONCLUSION: PPGD is a useful resource for studying scuticociliates or scuticociliatosis. We will continue to update the PPGD by integrating more data and aim to integrate the PPGD with other ciliate databases to build a comprehensive ciliate genome database. BioMed Central 2018-09-14 /pmc/articles/PMC6137885/ /pubmed/30217145 http://dx.doi.org/10.1186/s12864-018-5046-6 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Database
Wei, Wei
Chen, Kai
Miao, Wei
Yang, Wentao
Xiong, Jie
Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title_full Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title_fullStr Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title_full_unstemmed Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title_short Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
title_sort pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens
topic Database
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137885/
https://www.ncbi.nlm.nih.gov/pubmed/30217145
http://dx.doi.org/10.1186/s12864-018-5046-6
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