Cargando…

Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer

BACKGROUND: Recently, many potential prognostic biomarkers for gastric cancer (GC) have been identified, but the prognosis of advanced GC patients remains poor. Chloride channels are promising cancer biomarkers, and their family member chloride channel-3 (CLC-3) is involved in multiple biological be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Zhuoyu, Li, Yixin, Yang, Xiaoya, Yu, Meisheng, Chen, Zhanru, Zhao, Chan, Chen, Lixin, Wang, Liwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137920/ https://www.ncbi.nlm.nih.gov/pubmed/30217218 http://dx.doi.org/10.1186/s13045-018-0660-y

Ejemplares similares

Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients
por: Liu, Zhendong, et al.
Publicado: (2021)

ClC-3/SGK1 regulatory axis enhances the olaparib-induced antitumor effect in human stomach adenocarcinoma
por: Gu, Zhuoyu, et al.
Publicado: (2020)

Overexpression of ClC-3 Chloride Channel in Chondrosarcoma: An In Vivo Immunohistochemical Study with Tissue Microarray
por: Deng, Zhiqin, et al.
Publicado: (2019)

The ClC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis
por: Zhang, Haifeng, et al.
Publicado: (2013)

Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma
por: Lee, I-Neng, et al.
Publicado: (2021)

Overexpression of DGKI in Gastric Cancer Predicts Poor Prognosis
por: Huang, Chao, et al.
Publicado: (2020)

The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma
por: Li, Yixin, et al.
Publicado: (2022)

Association of XRCC1, XRCC2 and XRCC3 Gene Polymorphism with Esophageal Cancer Risk
por: Kaur, Jagjeet, et al.
Publicado: (2020)

Prognostic significance of XRCC4 expression in hepatocellular carcinoma
por: Lu, Jun, et al.
Publicado: (2017)

Involvement of the Tubular ClC-Type Exchanger ClC-5 in Glomeruli of Human Proteinuric Nephropathies
por: Ceol, Monica, et al.
Publicado: (2012)

Overexpression of chloride channel-3 (ClC-3) is associated with human cervical carcinoma development and prognosis
por: Guan, Yu-tao, et al.
Publicado: (2019)

Cysteine Modification of a Putative Pore Residue in Clc-0: Implication for the Pore Stoichiometry of Clc Chloride Channels
por: Lin, Chia-Wei, et al.
Publicado: (2000)

Systematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer
por: Yu, Yang, et al.
Publicado: (2023)

Functional coupling of chloride–proton exchanger ClC-5 to gastric H(+),K(+)-ATPase
por: Takahashi, Yuji, et al.
Publicado: (2013)

Significant value of XRCC2 and XRCC9 expression in the prognosis of human ovarian carcinoma
por: Liu, Yi, et al.
Publicado: (2021)

Cysteine Accessibility in ClC-0 Supports Conservation of the ClC Intracellular Vestibule
por: Engh, Anita M., et al.
Publicado: (2005)

Functional coupling of V-ATPase and CLC-5
por: Satoh, Nobuhiko, et al.
Publicado: (2017)

A Meta-Analysis for Association of XRCC1, XRCC2 and XRCC3 Polymorphisms with Susceptibility to Thyroid Cancer
por: Mandegari, Mohammad, et al.
Publicado: (2021)

PRDX4 overexpression is associated with poor prognosis in gastric cancer
por: Park, Sun Yi, et al.
Publicado: (2020)

Clinicopathologic and Prognostic Significance of Thymopoietin-α Overexpression in Gastric Cancer
por: Sun, Ding-Ping, et al.
Publicado: (2019)

ClC chloride channels
por: Mindell, Joe, et al.
Publicado: (2001)

Overexpression of CXXC5 is a strong poor prognostic factor in ER+ breast cancer
por: Fang, Lei, et al.
Publicado: (2018)

Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma
por: Jin, Jingchun, et al.
Publicado: (2012)

Overexpression of NEK3 is associated with poor prognosis in patients with gastric cancer
por: Cao, Yongfeng, et al.
Publicado: (2018)

Proton block of the CLC-5 Cl(−)/H(+) exchanger
por: Picollo, Alessandra, et al.
Publicado: (2010)

Cyclin D1 Serves as a Poor Prognostic Biomarker in Stage I Gastric Cancer
por: Go, Se-Il, et al.
Publicado: (2022)

KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance
por: Xu, Wenxia, et al.
Publicado: (2018)

Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer
por: Chen, Di, et al.
Publicado: (2018)

ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer
por: Vaezi, Alec, et al.
Publicado: (2011)

Prognostic value of CAPZA1 overexpression in gastric cancer
por: LEE, YOUNG-JOON, et al.
Publicado: (2013)

Conformational Changes in the Pore of CLC-0
por: Accardi, Alessio, et al.
Publicado: (2003)

Chloride Channelopathies of ClC-2
por: Bi, Miao Miao, et al.
Publicado: (2013)

Research and progress on ClC-2
por: Wang, Hongwei, et al.
Publicado: (2017)

ATP Inhibition of CLC-1 Is Controlled by Oxidation and Reduction
por: Zhang, Xiao-Dong, et al.
Publicado: (2008)

GlialCAM, a CLC-2 Cl(-) Channel Subunit, Activates the Slow Gate of CLC Chloride Channels
por: Jeworutzki, Elena, et al.
Publicado: (2014)

ClC1 chloride channel in myotonic dystrophy type 2 and ClC1 splicing in vitro
por: URSU, SIMONA-FELICIA, et al.
Publicado: (2012)

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease
por: Reed, Anita A. C., et al.
Publicado: (2010)

XRCC7 rs#7003908 Polymorphism and Helicobacter pylori Infection-Related Gastric Antrum Adenocarcinoma
por: Wang, Chao, et al.
Publicado: (2013)

Trop2 is overexpressed in gastric cancer and predicts poor prognosis
por: Zhao, Wei, et al.
Publicado: (2015)

GPR116 overexpression correlates with poor prognosis in gastric cancer
por: Zheng, Tian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2fqib834s4ug8imsamjjtlm3dl