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Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production
BACKGROUND: The involvement of inflammasome activation and macrophage polarization during the process of syphilis infection remains unknown. In this study, A series of experiments were performed using human macrophages to research the role of NLRP3 inflammasome regulation in interleukin (IL)-1β prod...
Autores principales: | Lin, Li-Rong, Liu, Wei, Zhu, Xiao-Zhen, Chen, Yu-Yan, Gao, Zheng-Xiang, Gao, Kun, Tong, Man-Li, Zhang, Hui-Lin, Xiao, Yao, Li, Wen-Dong, Li, Shu-Lian, Lin, Hui-Ling, Liu, Li-Li, Fang, Zan-Xi, Niu, Jian-Jun, Lin, Yong, Yang, Tian-Ci |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137923/ https://www.ncbi.nlm.nih.gov/pubmed/30217146 http://dx.doi.org/10.1186/s12865-018-0265-9 |
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